Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx241728
tested applications
ELISA, WB, IHC
Description
ALDH3B1 Antibody is a Rabbit Polyclonal against ALDH3B1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/200 - 1/1000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43353 |
| Gene ID | 221 |
| Alias | ALDH3B1,ALDH7,Aldehyde dehydrogenase 7 |
| Background | Antibody anti-ALDH3B1 |
| Status | RUO |
Descripción
ALDH3B1 is a cytosolic enzyme involved in the detoxification of reactive aldehydes generated from lipid peroxidation and environmental toxins. It is expressed in various tissues, including the liver, kidneys, and lungs, where it plays a protective role against oxidative stress and aldehyde-induced cellular damage. ALDH3B1 contributes to cellular homeostasis by metabolizing toxic aldehydes such as formaldehyde and 4-HNE, reducing protein and DNA adduct formation. Dysregulation of ALDH3B1 has been linked to metabolic and neurodegenerative disorders, where impaired aldehyde detoxification exacerbates oxidative damage. In cancer, ALDH3B1 has been identified as a tumor suppressor in certain contexts, as its activity reduces cellular oxidative stress and inhibits tumor progression. Recent studies suggest its involvement in maintaining redox balance and preventing aldehyde-associated toxicity in tissues exposed to oxidative or environmental stressors.
Related Products
anti- ALDH3B1 antibody
Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation.
Ver Producto
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
Rabbit polyclonal antibody against ALDH3B1 protein. Immunogen region is Internal.
Ver Producto
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
ALDH3B1 Antibody is a Rabbit Polyclonal against ALDH3B1.
Ver Producto