Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Antibody
169€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx322344
Tested Applications
ELISA, WB, IHC
Description
ALDH1A2 Antibody is a Rabbit Polyclonal against ALDH1A2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Immunogen: Recombinant human Retinal dehydrogenase 2 protein (1-180AA). |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O94788 |
| Gene ID | 8854 |
| NCBI Accession | NP_001193826.1, NM_001206897.1, NP_003879.2, NM_003888.3 |
| OMIM | 603687 |
| Alias | RALDH 2,RalDH2,Retinaldehyde specific dehydrogenase type 2 |
| Background | Antibody anti-ALDH1A2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ALDH1A2, like ALDH1A1, catalyzes the conversion of retinaldehyde to retinoic acid, a critical molecule for regulating gene expression during embryonic development and organogenesis. ALDH1A2 is highly expressed during early development, particularly in tissues forming the heart, lungs, and nervous system, where it regulates retinoic acid signaling pathways essential for proper patterning and differentiation. Loss-of-function mutations in ALDH1A2 lead to congenital disorders, including congenital diaphragmatic hernia, cardiac anomalies, and craniofacial defects, due to disrupted retinoic acid gradients during development. In adults, ALDH1A2 plays a role in maintaining tissue homeostasis and regulating inflammatory responses. Its dysregulation has been linked to metabolic disorders, such as obesity and insulin resistance, as well as fibrotic diseases. ALDH1A2 is also studied in cancer biology for its role in tumor growth suppression through retinoic acid-mediated differentiation and cell cycle control.
Productos relacionados
Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Antibody
ALDH1A2 Antibody is a Rabbit Polyclonal Antibody against ALDH1A2.…
Ver producto
Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Antibody
Rabbit polyclonal antibody against ALDH1A2 protein. Immunogen region is C-terminal.…
Ver producto Aldehyde Dehydrogenase 1 Family Member A2 (ALDH1A2) Antibody
Rabbit Polyclonal against the ALDH1A2 protein.…
Ver producto