Alcohol Dehydrogenase 6 (Class V) (ADH6) Antibody

Este producto es parte de ADH - Alcohol dehydrogenase
Alcohol Dehydrogenase 6 (Class V) (ADH6) Antibody

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-ADH6

proveedor

Abbexa

reference

abx034276

Tested Applications

ELISA, WB, IHC, FCM

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

ADH6 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site.


Background

ADH6 encodes a class V alcohol dehydrogenase, which is expressed in the liver and other tissues but is less well characterized compared to other members of the ADH family. It is believed to participate in the oxidation of ethanol and other alcohols, although its specific substrates and physiological roles remain under investigation. ADH6 shows structural similarities to other ADH enzymes, suggesting potential roles in detoxification and metabolism of alcohols and aldehydes. While its contribution to overall alcohol metabolism may be limited, it may have tissue-specific functions in metabolic pathways. Emerging studies suggest that genetic variations in ADH6 could influence individual differences in alcohol tolerance and susceptibility to alcohol-related disorders. Its role in cellular detoxification processes highlights its potential importance in maintaining metabolic balance and protecting against alcohol-induced oxidative stress. Further research is needed to fully elucidate the functional significance of ADH6 in human physiology.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Alcohol Dehydrogenase 6 (Class V) (ADH6)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC, FCM


purification

Purified Rabbit Polyclonal Antibody.


recommended dilution

WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ADH6


dry ice

No


availability

Shipped within 5-10 working days.


alias

ADH-5


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