Alcohol Dehydrogenase 6 (Class V) (ADH6) Antibody
292.5€ (80 µl)
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935106861
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name
Alcohol Dehydrogenase 6 (Class V) (ADH6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034276
tested applications
ELISA, WB, IHC, FCM
Description
ADH6 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alcohol Dehydrogenase 6 (Class V) (ADH6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28332 |
| Alias | ADH-5 |
| Background | Antibody anti-ADH6 |
| Status | RUO |
Descripción
ADH6 encodes a class V alcohol dehydrogenase, which is expressed in the liver and other tissues but is less well characterized compared to other members of the ADH family. It is believed to participate in the oxidation of ethanol and other alcohols, although its specific substrates and physiological roles remain under investigation. ADH6 shows structural similarities to other ADH enzymes, suggesting potential roles in detoxification and metabolism of alcohols and aldehydes. While its contribution to overall alcohol metabolism may be limited, it may have tissue-specific functions in metabolic pathways. Emerging studies suggest that genetic variations in ADH6 could influence individual differences in alcohol tolerance and susceptibility to alcohol-related disorders. Its role in cellular detoxification processes highlights its potential importance in maintaining metabolic balance and protecting against alcohol-induced oxidative stress. Further research is needed to fully elucidate the functional significance of ADH6 in human physiology.
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