Aflibercept is a recombinant fusion protein biosimilar expressed in CHO cells, targeting VEGFA, Aflibercept is a manufactured protein that acts as a decoy receptor for all VEGF-A isoforms and placental growth factor. This agent was engineered through fusion of the ligand-binding domains from two VEGF receptors with the constant region of IgG1, resulting in high-affinity VEGF binding and prevention of VEGF pathway activation.
Biosimilars
Human
Monoclonal
Human
VEGFA
Human
IgG1
Unconjugated
Liquid
ELISA, WB
100 µg
1 mg
Recombinant
> 95%
Purified from cell culture supernatants by Protein A/G chromatography.
0.01 M PBS. pH 7.4.
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
No
Shipped within 7-12 working days.
Biosimilars
CAS Number 862111-32-8
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