Adrenomedullin (ADM) Antibody
260€ (50 µl)
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935106861
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name
Adrenomedullin (ADM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211718
tested applications
ELISA, WB, IHC
Description
ADM Antibody is a Rabbit Polyclonal against ADM.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adrenomedullin (ADM) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, WB: 1/200 - 1/1000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35318 |
| Gene ID | 133 |
| Alias | AM,PAMP |
| Background | Antibody anti-ADM |
| Status | RUO |
Descripción
Adrenomedullin (ADM) is a peptide hormone that is primarily secreted by various tissues, including the adrenal medulla, vascular endothelium, heart, lungs, and kidneys. Adrenomedullin is a 52-amino acid peptide hormone derived from a larger precursor protein called preproadrenomedullin. It belongs to the calcitonin gene-related peptide (CGRP) family and shares structural similarities with calcitonin and calcitonin gene-related peptide. Adrenomedullin plays a crucial role in regulating vascular tone, blood pressure, and cardiovascular homeostasis by promoting vasodilation and inhibiting vasoconstriction. Additionally, adrenomedullin exhibits anti-inflammatory, anti-apoptotic, and angiogenic properties, contributing to tissue protection and repair.Adrenomedullin binds to specific receptors known as adrenomedullin receptors (ADMR), which are coupled to G proteins
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