Adiponectin Receptor 1 (ADIPOR1) Antibody (Biotin)

Este producto es parte de ADIPOR - Adiponectin receptor
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169€ (20 µg)

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935106861
info@markelab.com
name
Adiponectin Receptor 1 (ADIPOR1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx314733
tested applications
ELISA

Description

ADIPOR1 Antibody (Biotin) is a Rabbit Polyclonal against ADIPOR1 conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdiponectin Receptor 1 (ADIPOR1)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationBiotin
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ96A54
Gene ID51094
OMIM607945
AliasACDCR1,CGI-45,CGI45,PAQR1
BackgroundAntibody anti-ADIPOR1
StatusRUO

The adiponectin receptor (ADIPOR) is a cell surface receptor that mediates the biological effects of adiponectin, a protein hormone secreted by adipose tissue. There are two known types of adiponectin receptors, named adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2). These receptors are encoded by the ADIPOR1 and ADIPOR2 genes, respectively. Adiponectin receptors belong to the class of seven-transmembrane domain receptors, also known as G protein-coupled receptors (GPCRs). They have an extracellular N-terminus, seven transmembrane helices, and an intracellular C-terminus. ADIPOR1 and ADIPOR2 exhibit distinct tissue distribution and signal transduction mechanisms. Adiponectin receptors specifically bind to adiponectin, allowing the hormone to exert its effects on target cells. Adiponectin exists in different oligomeric forms, including trimeric, hexameric, and high-molecular-weight complexes, and can interact with both ADIPOR1 and ADIPOR2. Activation of adiponectin receptors triggers intracellular signaling pathways that regulate various physiological processes, including glucose metabolism, fatty acid oxidation, insulin sensitivity, and anti-inflammatory responses.

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