Adiponectin Receptor 1 (ADIPOR1) Antibody

Este producto es parte de ADIPOR - Adiponectin receptor
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169€ (20 µg)

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935106861
info@markelab.com
name
Adiponectin Receptor 1 (ADIPOR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302569
tested applications
ELISA, WB, IHC, IF/ICC

Description

ADIPOR1 Antibody is a Rabbit Polyclonal against ADIPOR1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Adiponectin Receptor 1 (ADIPOR1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96A54
Gene ID
51094
OMIM
607945
Alias
ACDCR1,CGI-45,CGI45,PAQR1
Background
Antibody anti-ADIPOR1
Status
RUO

Descripción

The adiponectin receptor (ADIPOR) is a cell surface receptor that mediates the biological effects of adiponectin, a protein hormone secreted by adipose tissue. There are two known types of adiponectin receptors, named adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2). These receptors are encoded by the ADIPOR1 and ADIPOR2 genes, respectively. Adiponectin receptors belong to the class of seven-transmembrane domain receptors, also known as G protein-coupled receptors (GPCRs). They have an extracellular N-terminus, seven transmembrane helices, and an intracellular C-terminus. ADIPOR1 and ADIPOR2 exhibit distinct tissue distribution and signal transduction mechanisms. Adiponectin receptors specifically bind to adiponectin, allowing the hormone to exert its effects on target cells. Adiponectin exists in different oligomeric forms, including trimeric, hexameric, and high-molecular-weight complexes, and can interact with both ADIPOR1 and ADIPOR2. Activation of adiponectin receptors triggers intracellular signaling pathways that regulate various physiological processes, including glucose metabolism, fatty acid oxidation, insulin sensitivity, and anti-inflammatory responses.

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