Adiponectin glycosilated, HMW Rich Protein
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Description
Adiponectin glycosilated, HMW Rich Protein is a recombinant cytokine expressed in HEK cells. It is a single, glycosylated, polypeptide chain.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acrp30 HMW |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: 19-244 AA. |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Purification | 0.4 µm filtered prior to lyophilization. |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, pH 7.5, containing 50 mM NaCl and 1 mM CaCl2. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store lyophilized at -20 °C. Upon reconstitution, aliquot and store at -20 °C. Reconstituted aliquots can be stored at 4°C for short-term storage. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15848 |
| Gene ID | 9370 |
| Alias | ADIPOQ,ACDC,ACRP30,ADPN, APM-1, GBP28, adiponectin, C1Q and collagen domain containing |
| Background | Protein ADIPOQ |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Concentration: Prior to lyophilization: 0.5 mg/ml |
Descripción
Adiponectin (ADIPOQ) is a hormone and adipokine whch is produced and secreted by adipocytes. It plays a significant role in regulating several metabolic processes , including glucose regulation and fatty acid oxidation. Adiponectin levels are inversely correlated with obesity. Adiponectin enhances insulin sensitivity, which means it helps to respond better to insulin and regulate blood sugar levels more effectively. Low levels of adiponectin are associated with insulin resistance, a key feature of type 2 diabetes. Adiponectin has anti-inflammatory properties, helping to reduce inflammation in various tissues and organs. Chronic inflammation is implicated in the development of several diseases, including cardiovascular disease and metabolic syndrome. Adiponectin is thought to have protective effects on the cardiovascular system. It can help prevent the development of atherosclerosis (hardening of the arteries) by reducing the buildup of plaque in the blood vessels Adiponectin also plays a role in the regulation of energy metabolism by promoting the oxidation of fatty acids in muscle tissue and the liver. This helps to prevent the accumulation of fat in tissues.
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