Adhesion G Protein-Coupled Receptor L2 (ADGRL2) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor L2 (ADGRL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326801
tested applications
ELISA, IHC, IF/ICC
Description
LPHN2 Antibody is a Rabbit Polyclonal against LPHN2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor L2 (ADGRL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/5000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95490 |
| Gene ID | 23266 |
| Alias | ADGRL2,LPHN2,latrophilin 2,LPHH1,latrophilin homologue in humans 1,LEC1,lectomedin-1,CIRL2,calcium-independent receptor of alpha-latrotoxin 2,CL2,LEC1,LPHH1 |
| Background | Antibody anti-ADGRL2 |
| Status | RUO |
Descripción
ADGRL2, or Latrophilin-2, is expressed across neuronal tissues and gastrointestinal organs, where it facilitates cellular adhesion and communication. Through its interaction with extracellular ligands and other adhesion molecules, ADGRL2 regulates synaptic formation, tissue organization, and intracellular signaling. This receptor is particularly significant in the gastrointestinal tract, where it contributes to tissue integrity and functional coordination. Its presence in neural tissues suggests a role in neurodevelopmental processes, synaptic organization, and intercellular signaling. ADGRL2’s involvement in cell adhesion mechanisms also suggests roles in maintaining homeostasis within epithelial and neuronal environments. Dysregulation or mutation of ADGRL2 has been associated with neurodevelopmental delays, gastrointestinal disorders, and altered cellular communication, making it a key target for research into both developmental and systemic diseases.
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