Adhesion G Protein-Coupled Receptor E7 (ADGRE5) Antibody (PE)
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Description
Adhesion G Protein-Coupled Receptor E5 (ADGRE5) Antibody (PE) is a PE-conjugated Mouse monoclonal antibody for Adhesion G Protein-Coupled Receptor E5 (ADGRE5).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor E5 (ADGRE5) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 |
| Clone ID | Q810 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C in the dark. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P48960 |
| Gene ID | 976 |
| Alias | ADGRE5,CD97,BL-Ac (F2),CD97,TM7LN1 |
| Background | Antibody anti-ADGRE5 |
| Status | RUO |
Descripción
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ADGRE5 antibody
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
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