Adenylate Kinase Isoenzyme 5 (AK5) Antibody (Biotin)
169€ (20 µg)
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Name
Adenylate Kinase Isoenzyme 5 (AK5) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx315182
Tested Applications
ELISA
Description
AK5 Antibody (Biotin) is a Rabbit Polyclonal against AK5 conjugated to Biotin.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Kinase Isoenzyme 5 (AK5) Immunogen: Recombinant Human Adenylate kinase isoenzyme 5 protein (61-215AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y6K8 |
| Gene ID | 26289 |
| NCBI Accession | NP_036225.2, NM_012093.3, NP_777283.1, NM_174858.2 |
| OMIM | 608009 |
| Alias | AK6 |
| Background | Antibody anti-AK5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AK5 is a cytosolic adenylate kinase predominantly expressed in the brain, where it plays a role in neural energy metabolism and synaptic function. Unlike other AK isoforms, AK5 demonstrates substrate specificity for ATP/GTP and AMP. It is thought to regulate energy transfer and storage in neurons, particularly in response to neurotransmission demands. AK5 expression correlates with cognitive functions, and its dysfunction has been implicated in neurodevelopmental disorders and memory deficits. AK5 has been shown to influence energy-sensing pathways, such as AMPK, thereby contributing to neuronal survival during energy depletion.
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