Adenylate cyclase type 10 (ADCY10) Antibody
169€ (20 µl)
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Name
Adenylate cyclase type 10 (ADCY10) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx348216
Tested Applications
ELISA, IHC
Description
Adenylate cyclase type 10 (ADCY10) Antibody is a Rabbit Polyclonal antibody for the detection of Human ADCY10.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate cyclase type 10 (ADCY10) Immunogen: Recombinant Human Adenylate cyclase type 10 protein (897-1136 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96PN6 |
| OMIM | 143870 |
| Alias | HCA2,HEL-S-7a,SAC,SACI,Sacy |
| Background | Antibody anti-ADCY10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY10, also known as soluble adenylate cyclase (sAC), differs from other ADCY isoforms as it is soluble and not membrane-bound. It is activated by bicarbonate ions and calcium, making it essential for pH and metabolic regulation. ADCY10 is involved in processes such as sperm motility, capacitation, and fertilization in the reproductive system. It also regulates cellular metabolism, mitochondrial respiration, and renal acid-base homeostasis. Mutations in ADCY10 have been associated with male infertility and metabolic dysfunctions, underscoring its significance in reproductive and cellular physiology.
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