Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Antibody

Este producto es parte de ACADM - Acyl-CoA Dehydrogenase C-4 To C-12 Straight Chain
Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Antibody

Pida mas información

935106861

info@markelab.com

Precio

286€ (100 µl)

Antibody anti-ACADM

proveedor

Abbexa

reference

abx131296

Tested Applications

WB, IHC, IF/ICC

reactivity

Mouse

status

RUO

clonality

Polyclonal

Descripción

ACADM Antibody is a Rabbit Polyclonal against ACADM.


Background

The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Mouse


immunogen target

Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC, IF/ICC


purification

Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.


recommended dilution

WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.


size 1

100 µl


size 2

200 µl


size 3

1 ml


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ACADM


dry ice

No


availability

Shipped within 5-7 working days.


alias

ACAD1,MCAD,MCADH


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