Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody

Este producto es parte de ACSL - Acyl-CoA Synthetase Long-Chain Family Member Elisa - Clia - Antibody - Protein
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416€ (200 µl)

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935106861
info@markelab.com
name
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432276
tested applications
P-ELISA, WB, IHC

Description

ACSL5 Antibody is a Goat Polyclonal antibody against ACSL5.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IHC
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
51703
NCBI Accession
NP_057318.2, NP_976313.1, NP_976314.1
Alias
ACS2,ACS5,DIAR13,FACL5
Background
Antibody anti-ACSL5
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

ACSL5 is a mitochondrial and cytosolic enzyme that activates long-chain fatty acids, particularly those with a preference for saturated and monounsaturated fatty acids, by converting them into acyl-CoA derivatives. ACSL5 is expressed in tissues like the small intestine, liver, and skeletal muscle, where it supports energy production, lipid absorption, and storage. This enzyme plays a crucial role in directing fatty acids toward oxidation or triglyceride synthesis, depending on metabolic demands, and is essential for maintaining energy homeostasis during fasting or high-fat diets. Dysregulation of ACSL5 has been implicated in metabolic disorders, such as obesity, diabetes, and non-alcoholic fatty liver disease, as altered fatty acid activation can lead to lipid accumulation and insulin resistance. ACSL5’s dual localization and specificity underscore its adaptability in regulating systemic and cellular lipid metabolism under diverse metabolic conditions.

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