Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (ACADS) Antibody

Background

The ACADS gene encodes the enzyme acyl-CoA dehydrogenase short chain, a tetrameric mitochondrial flavoprotein involved in the initial step of the mitochondrial fatty acid beta-oxidation pathway. This enzyme belongs to the acyl-CoA dehydrogenase family and is crucial for metabolizing short-chain fatty acids. Mutations in the ACADS gene have been linked to short-chain acyl-CoA dehydrogenase (SCAD) deficiency, a metabolic disorder. Alternative splicing of this gene produces two variants encoding different isoforms of the enzyme.