Acyl-CoA Binding Domain Containing 3 (ACBD3) Antibody

169€ (20 µg)
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935106861
info@markelab.com
name
Acyl-CoA Binding Domain Containing 3 (ACBD3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx338869
tested applications
ELISA, WB, IHC, IF/ICC
Description
ACBD3 Antibody is a Rabbit Polyclonal against ACBD3.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Acyl-CoA Binding Domain Containing 3 (ACBD3) |
Host | Rabbit |
Reactivity | Human, Rat |
Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/300 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9H3P7 |
Gene ID | 64746 |
Alias | ACBD3,GCP60,GOCAP1,GOLPH1 PAP7,Golgi resident protein GCP60 |
Background | Antibody anti-ACBD3 |
Status | RUO |
Descripción
ACBD3 is a multifunctional protein involved in lipid metabolism, vesicular trafficking, and organelle function. It contains an acyl-CoA binding domain, allowing it to interact with fatty acyl-CoA molecules and regulate lipid transport and metabolism. ACBD3 is also known for its role in maintaining Golgi apparatus integrity and functioning as an adaptor protein, facilitating interactions between Golgi membranes and other cellular components. It participates in steroidogenesis by supporting mitochondrial cholesterol trafficking, a critical step in steroid hormone synthesis. ACBD3’s interactions with viral proteins have been implicated in host-pathogen interactions, making it a target of interest in virology. Dysregulation of ACBD3 has been associated with Golgi fragmentation, disrupted lipid metabolism, and diseases such as cancer and neurodegenerative disorders.
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