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ACVR1 Antibody (Biotin)
Pida mas información
935106861
info@markelab.com
Precio
387.5€ (200 µl)
Antibody anti-ACVR1
proveedor
Abbexareference
abx431072Tested Applications
P-ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ACVR1 Antibody is a Goat Polyclonal antibody against ACVR1.
Background
ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
ACVR1
host
Goat
conjugation
Biotin
form
Liquid
tested applications
P-ELISA, WB, IHC
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACVR1
dry ice
No
availability
Shipped within 1-3 working days.
alias
ACVRLK2
gene id
NCBI accession
NP_001096.1
note
This product is for research use only.
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