Activin A Receptor Type 2A (ACVR2A) Antibody

Este producto es parte de ACVR - Activin A Receptor Type
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286€ (100 µl)

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935106861
info@markelab.com
name
Activin A Receptor Type 2A (ACVR2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171068
tested applications
WB, IHC, IF/ICC

Description

Activin A Receptor Type II A (ACVR2A) Antibody is a Mouse Monoclonal antibody against Activin A Receptor Type II A (ACVR2A).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Activin A Receptor Type 2A (ACVR2A)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ACVR2,Activin receptor type II,ACTR-IIA
Background
Antibody anti-ACVR2A
Status
RUO

Descripción

ACVR2A is a type II receptor that binds activin ligands and subsequently activates type I receptors like ACVR1B. This receptor is integral to TGF-β/activin signaling, mediating cellular processes like growth, differentiation, and apoptosis. ACVR2A is expressed in various tissues, particularly in the reproductive system. Mutations or loss of ACVR2A function are implicated in cancers such as colorectal carcinoma, where its absence disrupts normal cell cycle control and promotes tumor progression.

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