Human Activator of HSP90 ATPase-1 Protein (AHA1) Protein
Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein AHSA1
proveedor
Abbexareference
abx260390Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Activator of HSP90 ATPase-1 Protein (AHA1) is a recombinant heat shock protein expressed in E.coli.
Background
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Activator of HSP90 ATPase-1 Protein (AHA1)
host
E. coli
conjugation
Unconjugated
form
Liquid
tested applications
SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
1 mg
observerd MW
Molecular Weight: 36.1 kDa Concentration: 1 mg/ml Sequence Fragment: 19-337 AA.
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
20 mM Tris-HCl buffer, pH 8.0, containing 2 mM EDTA.
storage
Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
or code
AHSA1
dry ice
No
availability
Shipped within 5-10 working days.
alias
AHA1, C14orf3, hAha1, p38
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- AHSA1 antibody
proveedor
FineTestreference
FNab00232Tested Applications
ELISA, IHC, IF, WB, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalCochaperone that stimulates HSP90 ATPase activity(By similarity). May affect a step in the endoplasmic reticulum to Golg...
Precio a consultar
Ver másRecombinant Human AHA1
proveedor
FineTestreference
P4320Tested Applications
Western Blot，ELISAstatus
RUOPrecio a consultar
Ver másRecombinant Human AHSA2
proveedor
FineTestreference
P6078Tested Applications
Western Blot，ELISAstatus
RUOPrecio a consultar
Ver más