Human Activator of HSP90 ATPase-1 Protein (AHA1) Protein
234€ (10 µg)
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935106861
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name
Human Activator of HSP90 ATPase-1 Protein (AHA1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx260390
tested applications
SDS-PAGE
Description
Activator of HSP90 ATPase-1 Protein (AHA1) is a recombinant heat shock protein expressed in E.coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Activator of HSP90 ATPase-1 Protein (AHA1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: 36.1 kDa Concentration: 1 mg/ml Sequence Fragment: 19-337 AA. |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl buffer, pH 8.0, containing 2 mM EDTA. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95433 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Protein AHSA1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
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