Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) Antibody (HRP)
650€ (100 µg)
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935106861
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name
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx444823
tested applications
ELISA, WB, IHC, IF/ICC, IP
Description
AHA1 Antibody is a Rat Monoclonal against AHA1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) |
| Host | Rat |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/1000, IHC: 1/100, IF/ICC: 1/1000, IP: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | HRP |
| Isotype | IgG2a Kappa |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH7.2. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| Dry Ice | No |
| UniProt ID | Q8BK64 |
| Gene ID | 217737 |
| NCBI Accession | NP_666148.1 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Antibody anti-AHSA1 |
| Status | RUO |
| Note | Concentration: 1.2 mg/ml - |
Descripción
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
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