Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) Antibody (ATTO594)
663€ (100 µg)
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Name
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) Antibody (ATTO594)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx444788
Tested Applications
ELISA, WB, IHC, IF/ICC, IP
Description
AHA1 Antibody is a Rat Monoclonal against AHA1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHA1) Immunogen: Mouse Aha1. |
| Host | Rat |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Laser Line: 594 Excitation/Emission: 603/626 |
| Assay Type | Concentration: 1.59 mg/ml |
| Recommended Dilution | WB: 1/1000, IHC: 1/100, IF/ICC: 1/1000, IP: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | ATTO594 |
| Isotype | IgG2a Kappa |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH7.2. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at 4°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8BK64 |
| Gene ID | 217737 |
| NCBI Accession | NP_666148.1 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Antibody anti-AHSA1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
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