Actin, Cytoplasmic 1 (ACTB) Antibody
221€ (50 µg)
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Name
Actin, Cytoplasmic 1 (ACTB) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx326896
Tested Applications
ELISA, WB, IHC
Description
ACTB Antibody is a Rabbit Polyclonal against ACTB.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin, Cytoplasmic 1 (ACTB) Immunogen: Synthesized peptide derived from the N-terminal region of human Actin β. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/1000 - 1/4000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60709 |
| Gene ID | 60 |
| Alias | BKRNS,BNS,BRWS1,CSMH,DDS1,THC8 |
| Background | Antibody anti-ACTB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTB, also known as beta-actin, is a highly conserved protein that serves as a fundamental component of the cytoskeleton in eukaryotic cells. Beta-actin is involved in various cellular processes, including cell structure, motility, and intracellular transport. Beta-actin forms filamentous structures, along with other actin isoforms, which constitute the cytoskeleton. This dynamic network of filaments provides structural support to the cell and is involved in cell shape determination and mechanical stability, motility and migration. It participates in the formation of cell protrusions such as lamellipodia and filopodia, which are essential for cell movement. Beta-actin also plays a role in cell division, where it is involved in cytokinesis, the process of cell division following nuclear division. Furthermore, beta-actin is involved in intracellular transport processes, serving as a track for myosin motor proteins to transport cargo within the cell. This function is essential for the movement of vesicles, organelles, and other cellular components along the cytoskeleton.
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