Actin, Cytoplasmic 1 (ACTB) Antibody
52€ (10 µg)
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Name
Actin, Cytoplasmic 1 (ACTB) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx249494
Tested Applications
WB, IHC, IF/ICC
Description
Actin, Cytoplasmic 1 (ACTB) Antibody is a Mouse monoclonal against Actin, Cytoplasmic 1 (ACTB).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin, Cytoplasmic 1 (ACTB) Immunogen: The antiserum was produced against full-length Human Actin, Cytoplasmic 1 (ACTB). |
| Host | Mouse |
| Reactivity | Human, Monkey, Mouse, Rat, Hamster, Dog, Insect, Chicken |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/5000 - 1/10000, IHC: 1/200, IF/ICC: 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from mouse antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C for up to 1 year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60709 |
| Gene ID | 60 |
| OMIM | 102630 |
| Alias | BKRNS,BNS,BRWS1,CSMH,DDS1,THC8 |
| Background | Antibody anti-ACTB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTB, also known as beta-actin, is a highly conserved protein that serves as a fundamental component of the cytoskeleton in eukaryotic cells. Beta-actin is involved in various cellular processes, including cell structure, motility, and intracellular transport. Beta-actin forms filamentous structures, along with other actin isoforms, which constitute the cytoskeleton. This dynamic network of filaments provides structural support to the cell and is involved in cell shape determination and mechanical stability, motility and migration. It participates in the formation of cell protrusions such as lamellipodia and filopodia, which are essential for cell movement. Beta-actin also plays a role in cell division, where it is involved in cytokinesis, the process of cell division following nuclear division. Furthermore, beta-actin is involved in intracellular transport processes, serving as a track for myosin motor proteins to transport cargo within the cell. This function is essential for the movement of vesicles, organelles, and other cellular components along the cytoskeleton.
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