Abhydrolase Domain Containing 6 (ABHD6) Antibody
442€ (200 µl)
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935106861
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name
Abhydrolase Domain Containing 6 (ABHD6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432066
tested applications
P-ELISA
Description
ABHD6 Antibody is a Goat Polyclonal antibody against ABHD6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Abhydrolase Domain Containing 6 (ABHD6) Immunogen: abx615633 - Internal region: C-SEKSRYSLHQNMDK |
| Host | Goat |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 57406, 66082, 305795 |
| NCBI Accession | NP_065727.3 |
| Alias | ABHD6, Monoacylglycerol lipase ABHD6 |
| Background | Antibody anti-ABHD6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ABHD6 is a serine hydrolase that modulates lipid signaling by hydrolyzing monoacylglycerols, including 2-arachidonoylglycerol (2-AG), a key endocannabinoid. Through its regulation of 2-AG levels, ABHD6 influences cannabinoid receptor signaling, which affects processes such as pain perception, appetite, and inflammation. ABHD6 is expressed in multiple tissues, including the brain, pancreas, and immune cells, where it plays roles in synaptic activity, glucose homeostasis, and immune responses. It has also been implicated in neuroinflammation and metabolic disorders, with potential links to diseases such as Alzheimer’s and diabetes. Structurally, ABHD6’s hydrolase domain is specialized for monoacylglycerol hydrolysis, making it a key regulator of endocannabinoid tone. As a critical enzyme in lipid signaling and metabolism, ABHD6 is a promising therapeutic target for treating neurodegenerative diseases, metabolic conditions, and chronic pain.
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