Abhydrolase Domain Containing 12 (ABHD12) Antibody

Name: Abhydrolase Domain Containing 12 (ABHD12) Antibody
Brand: Abbexa
SKU: abx432196
Price: 416 EUR
Availability: OnlineOnly

Este producto es parte de ABHD - Abhydrolase Domain Containing

Pida mas información

935106861

info@markelab.com

Precio

416€ (200 µl)

Antibody anti-ABHD12

proveedor

Abbexa

reference

abx432196

Tested Applications

P-ELISA, WB

reactivity

Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

ABHD12 Antibody is a Goat Polyclonal antibody against ABHD12.

Background

ABHD12 (Abhydrolase Domain Containing 12) is a membrane-bound serine hydrolase primarily involved in lipid metabolism and neuroinflammatory regulation. It plays a critical role in degrading lysophosphatidylserine (lyso-PS), a bioactive lipid mediator involved in immune signaling. ABHD12 is highly expressed in the brain and other tissues, where it regulates lipid signaling pathways crucial for neural function and homeostasis. Mutations in the ABHD12 gene are associated with PHARC syndrome (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataracts), a neurodegenerative disorder. This enzyme’s activity is essential for maintaining balanced lipid signaling and protecting against neuroinflammation and neurodegeneration.

Características del producto

clonality

Polyclonal

reactivity

Mouse, Rat

immunogen target

Abhydrolase Domain Containing 12 (ABHD12)

host

Goat

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

recommended dilution

P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ABHD12

dry ice

availability

Shipped within 5-10 working days.

alias

ABHD12A,BEM46L2,C20orf22,PHARC

gene id

https://www.ncbi.nlm.nih.gov/gene/26090 https://www.ncbi.nlm.nih.gov/gene/76192 https://www.ncbi.nlm.nih.gov/gene/499913

NCBI accession

NP_001035937.1, NP_056415.1

note

Concentration: 0.5 mg/ml -

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