A Disintegrin And Metalloprotease 22 (ADAM22) Antibody

286€ (100 µl)
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935106861
info@markelab.com
name
A Disintegrin And Metalloprotease 22 (ADAM22) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131305
tested applications
WB, IHC, IF/ICC
Description
ADAM22 Antibody is a Rabbit Polyclonal against ADAM22.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | A Disintegrin And Metalloprotease 22 (ADAM22) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9P0K1 |
Gene ID | 53616 |
OMIM | 603709 |
Alias | MDC2,Disintegrin And Metalloproteinase Domain-Containing Protein 22,DEE61,EIEE61,adam-22 |
Background | Antibody anti-ADAM22 |
Status | RUO |
Note | Concentration: 0.74 mg/ml - |
Descripción
ADAM22 is a member of the ADAM (A Disintegrin And Metalloprotease domain) family, a group of membrane-anchored proteins structurally akin to snake venom disintegrins. These proteins play roles in of biological processes, orchestrating cell-cell and cell-matrix interactions such as fertilization, muscle development, and neurogenesis. Particularly abundant in the brain, ADAM22 likely serves as an integrin ligand within this organ. Its genetic makeup is subject to alternative splicing, yielding various transcript variants. Notably, ADAM22 exhibits interactions with DLG4, a member of the membrane-associated guanylate kinase (MAGUK) family, further expanding its functional repertoire within neural contexts.
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