A Disintegrin And Metalloprotease 20 (ADAM20) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
A Disintegrin And Metalloprotease 20 (ADAM20) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211418
tested applications
ELISA, WB, IHC
Description
ADAM20 Antibody is a Rabbit Polyclonal against ADAM20.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | A Disintegrin And Metalloprotease 20 (ADAM20) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/500 - 1/1000, WB: 1/100 - 1/500, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43506 |
| Gene ID | 8748 |
| Alias | EC 3.4.24.58, EC 3.4.24,A Disintegrin And Metalloproteinase Domain 20,adam-20 |
| Background | Antibody anti-ADAM20 |
| Status | RUO |
Descripción
ADAM20 (A Disintegrin And Metalloproteinase 20) is a member of the ADAM family. These proteins are primarily involved in various biological processes, including cell adhesion, migration, proteolysis, and signaling. ADAM20 is a type I transmembrane glycoprotein with a complex structure consisting of several distinct domains, including a metalloproteinase domain, disintegrin domain, cysteine-rich domain, epidermal growth factor-like domain, transmembrane domain, and cytoplasmic tail. The metalloproteinase domain of ADAM20 suggests its potential involvement in proteolytic processing of proteins within the extracellular matrix or on the cell surface. However, the specific functions and substrates of ADAM20 are not as well characterized compared to some other members of the ADAM family. ADAM20 is specifically implicated in reproductive biology, particularly in sperm development and function. It is one of the several ADAM proteins that play critical roles in fertilization.
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