26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

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383.5€ (100 µl)

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935106861
info@markelab.com
name
26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224302
tested applications
ELISA, WB, IHC, IF/ICC, FCM

Description

26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody is a Mouse Monoclonal against 26S Proteasome Regulatory Subunit 6A (PSMC3). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
26S Proteasome Regulatory Subunit 6A (PSMC3)
Host
Mouse
Reactivity
Human, Monkey, Rat
Recommended Dilution
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Isotype
IgG1
Purification
Purified from ascites by Protein G chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC, FCM
Buffer
PBS, containing 0.05% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P17980
Gene ID
5702
NCBI Accession
NM_002804
OMIM
186852
Background
Antibody anti-PSMC3
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

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