Family main features
Neurotrimin (NTM) is a glycoprotein that belongs to the IgLON (immunoglobulin-like cell adhesion molecules containing O-linked glycosylation) family, which is part of the larger immunoglobulin superfamily (IgSF). NTM plays crucial roles in the nervous system, particularly in neuron-neuron and neuron-glial interactions. It is involved in the processes of cell adhesion, axonal growth, and synapse formation. The expression of NTM is predominantly found in the brain and spinal cord, with significant implications for neural development and plasticity.
Neurotrimin is a transmembrane protein characterized by its structural domains:
The glycosylation of NTM, particularly O-linked glycosylation, is essential for its proper folding, stability, and function. This post-translational modification also affects the adhesive properties and interactions of NTM.
Neurotrimin is one member of the IgLON family, which includes other related proteins such as:
These proteins share similar structural features, including Ig-like domains and glycosylation sites, and are involved in various cell adhesion processes within the nervous system.
Neurotrimin serves several critical functions in the nervous system:
Dysregulation or mutation of NTM has been linked to various neurological and psychiatric disorders:
Neurotrimin (NTM) is a critical glycoprotein of the IgLON family involved in various aspects of neural development and function. With its three Ig-like domains, NTM facilitates cell adhesion, axonal growth, synapse formation, and neuronal migration. Its proper functioning is vital for the establishment and maintenance of neural circuits and synaptic plasticity. Dysregulation or mutation of NTM is associated with a range of neurological and psychiatric disorders, including autism spectrum disorder, schizophrenia, neurodegenerative diseases, and certain cancers. Understanding the molecular mechanisms of NTM can provide insights into therapeutic strategies for these conditions.
neurotrimin (NTM)
HNT,NTRI,CEPU-1,IGLON2,IgLON family member 2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con NTM - neurotrimin
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 14 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NTM | abx555789 | Cow Neurotrimin (NTM) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q58DA5 | RUO | ||
Abbexa | NTM | abx490635 | Natamycin (NTM) CLIA Kit | General | Biological agents. | Competitive | 3.7 ng/ml - 300 ng/ml | < 1.45 ng/ml | 937.5 | 96 tests | RUO | |
Abbexa | NTM | abx258951 | Natamycin (NTM) ELISA Kit | General | Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernatants, Other biological fluids | Competitive | 24.69 pg/ml - 2000 pg/ml | < 9.45 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | NTM | abx555875 | Human Neurotrimin (NTM) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | Q9P121 | RUO | |
Abbexa | NTM | abx556087 | Mouse Neurotrimin (NTM) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | Q99PJ0 | RUO | |
Abbexa | NTM | abx555898 | Rat Neurotrimin (NTM) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | Q62718 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NTM | abx131464 | Natamycin (NTM) Antibody | General | Polyclonal | Rabbit | Natamycin (NTM) | Unconjugated | ELISA | 287.5 | 100 µl | RUO | ||
FineTest | NTM | FNab05885 | anti- NTM antibody | human | polyclonal | Rabbit | neurotrimin | IgG | Unconjugated | ELISA, WB | 100µg | Q9P121 | RUO | |
Abbexa | NTM | abx321203 | Neurotrimin (NTM) Antibody | Human | Polyclonal | Rabbit | Neurotrimin (NTM) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9P121 | RUO | |
Abbexa | NTM | abx324503 | Natamycin (NTM) Antibody | Human | Polyclonal | Rabbit | Natamycin (NTM) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q9P121 | RUO | |
Abbexa | NTM | abx322633 | Neurotrimin (NTM) Antibody | Human | Polyclonal | Rabbit | Neurotrimin (NTM) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | Q9P121 | RUO | |
Abbexa | NTM | abx235885 | Neurotrimin (NTM) Antibody | Human | Polyclonal | Rabbit | Neurotrimin (NTM) | Unconjugated | ELISA, WB | 350 | 100 µg | Q9P121 | RUO | |
Abbexa | NTM | abx123694 | Neurotrimin (NTM) Antibody | Human | Polyclonal | Rabbit | Neurotrimin (NTM) | Unconjugated | WB | 175 | 20 µl | Q9P121 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NTM | abx690726 | Human Neurotrimin (NTM) Protein | Human | Recombinant | Human | SDS-PAGE | 287.5 | 10 µg | Q9P121-3 | RUO |
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