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Lactosylceramide 4-Alpha-Galactosyltransferase, encoded by the A4GALT gene, is an enzyme involved in glycosphingolipid biosynthesis, specifically in the synthesis of glycosphingolipids containing the alpha-galactosyl residue. Catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system.
A4GALT catalyzes the transfer of a galactose residue from uridine diphosphate (UDP)-galactose to lactosylceramide, a precursor molecule, to form globotriaosylceramide (Gb3) or other glycosphingolipids containing alpha-galactosyl residues. This enzymatic reaction is a crucial step in the biosynthesis of various glycosphingolipids.
Glycosphingolipids are complex lipids found in cell membranes and play diverse roles in cell-cell recognition, signal transduction, membrane trafficking, and cell adhesion. The addition of alpha-galactosyl residues to lactosylceramide by A4GALT contributes to the structural diversity and functional complexity of glycosphingolipids. A4GALT is expressed in various tissues and cell types, including the liver, kidney, intestine, and immune cells. Its expression pattern may vary depending on developmental stage, tissue type, and physiological conditions.
Glycosphingolipids synthesized by A4GALT have important biological functions, including:
Mutations or dysregulation of A4GALT gene expression or enzymatic activity can lead to alterations in glycosphingolipid composition and structure, which may have clinical implications. Deficiencies or abnormalities in glycosphingolipids synthesized by A4GALT have been associated with certain diseases, including certain types of kidney disease, gastrointestinal disorders, and immune-related conditions.
Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT)
A4GALT,A14GALT,A4GALT1,Gb3S,P(k),P1,P1PK PK,alpha 1,4-galactosyltransferase,alpha 1,4-galactosyltransferase
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con A4GALT - Lactosylceramide 4-Alpha-Galactosyltransferase
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 18 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | A4GALT | abx385529 | Human Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 687.5 | 96 tests | Q9NPC4 | RUO |
Abbexa | A4GALT | abx500288 | Mouse Lactosylceramide 4-alpha-galactosyltransferase (A4GALT) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q67BJ4 | RUO | ||
Abbexa | A4GALT | abx500289 | Rat Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q9JI93 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | A4GALT | FNab00014 | anti- A4GALT antibody | human | polyclonal | Rabbit | alpha 1,4-galactosyltransferase | IgG | Unconjugated | ELISA, WB | 100µg | Q9NPC4 | RUO | |
Abbexa | A4GALT | abx038020 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | ELISA, IHC | 337.5 | 100 µg | Q9NPC4 | RUO | |
Abbexa | A4GALT | abx347154 | Globotriaosylceramide (CD77) Antibody (PE) | Human | Monoclonal | Rat | Globotriaosylceramide (CD77) | PE | FCM | 400 | 100 tests | RUO | ||
Abbexa | A4GALT | abx130539 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q9NPC4 | RUO | |
Abbexa | A4GALT | abx321328 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9NPC4 | RUO | |
Abbexa | A4GALT | abx347153 | Globotriaosylceramide (CD77) Antibody (FITC) | Human | Monoclonal | Rat | Globotriaosylceramide (CD77) | FITC | FCM | 350 | 100 tests | RUO | ||
Abbexa | A4GALT | abx230014 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | ELISA, WB | 350 | 100 µg | Q9NPC4, Q67BJ4 | RUO | |
Abbexa | A4GALT | abx123708 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | WB | 175 | 20 µl | Q9NPC4, Q67BJ4, Q9JI93 | RUO | |
Abbexa | A4GALT | abx242463 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9NPC4, Q9JI93 | RUO | |
Abbexa | A4GALT | abx242469 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Human | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9NPC4, Q9JI93 | RUO | |
Abbexa | A4GALT | abx130538 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Mouse | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q67BJ4 | RUO | |
Abbexa | A4GALT | abx130537 | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Antibody | Rat | Polyclonal | Rabbit | Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | Q9JI93 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | A4GALT | abx168869 | Mouse Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q67BJ4 | RUO |
Abbexa | A4GALT | abx168868 | Human Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9NPC4 | RUO |
Abbexa | A4GALT | abx168870 | Rat Lactosylceramide 4-Alpha-Galactosyltransferase (A4GALT) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | Q9JI93 | RUO |
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