Family main features
CD101, also known as IGSF2 (Immunoglobulin Superfamily Member 2), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is primarily expressed on a variety of immune cells, including T cells, dendritic cells, monocytes, and granulocytes. The gene encoding CD101 is located on chromosome 1. This molecule has been implicated in various immune regulatory functions and is believed to play a role in maintaining immune homeostasis and modulating immune responses.
CD101 is a complex molecule composed of several distinct domains:
CD101 is classified under the immunoglobulin superfamily due to its structure and sequence homology. Within this superfamily, it is categorized as a member of the Ig-like V-set domain containing proteins. There are no distinct subtypes of CD101 identified to date, but its expression pattern and function may vary depending on the cell type and the physiological or pathological context.
Immune Regulation:
Dendritic Cell Function:
Monocyte and Granulocyte Activity:
Regulatory T Cells:
Autoimmune Diseases:
Cancer:
Infectious Diseases:
Transplantation:
CD101 is an important immunomodulatory molecule with diverse roles in the immune system. Its structure, characterized by immunoglobulin-like domains, enables it to interact with various proteins and cells, modulating immune responses. CD101 is involved in regulating T cell activation, dendritic cell function, and the activity of monocytes and granulocytes. Its expression on regulatory T cells is crucial for maintaining immune tolerance.
Clinically, CD101 has been implicated in autoimmune diseases, cancer, infectious diseases, and transplantation. Altered expression or function of CD101 can impact immune regulation and contribute to disease pathogenesis. As a result, CD101 is a potential target for therapeutic strategies aimed at modulating immune responses in various clinical settings. Understanding the precise mechanisms of CD101 in immune regulation continues to be a critical area of research, offering insights into its potential as a therapeutic target.
CD101 molecule (CD101)
V7,IGSF2,EWI-101,Cell surface glycoprotein V7,Glu-Trp-Ile EWI motif-containing protein 101,Immunoglobulin superfamily member 2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con CD101 molecule
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 8 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | CD101 | abx528199 | Human Immunoglobulin superfamily member 2 (CD101) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q93033 | RUO | ||
Abbexa | CD101 | abx528200 | Mouse Immunoglobulin superfamily member 2 (CD101) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | A8E0Y8 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | CD101 | abx413874 | Immunoglobulin Superfamily Member 2 (CD101) Antibody | Human | Monoclonal | Mouse | Immunoglobulin Superfamily Member 2 (CD101) | Unconjugated | IHC, FCM, IP | 462.5 | 200 µg | Q93033 | RUO | |
Abbexa | CD101 | abx413875 | Immunoglobulin Superfamily Member 2 (CD101) Antibody (FITC) | Human | Monoclonal | Mouse | Immunoglobulin Superfamily Member 2 (CD101) | FITC | FCM | 400 | 100 µg | Q93033 | RUO | |
Abbexa | CD101 | abx323335 | Immunoglobulin Superfamily Member 2 (CD101) Antibody | Human | Polyclonal | Rabbit | Immunoglobulin Superfamily Member 2 (CD101) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q93033 | RUO | |
Abbexa | CD101 | abx413876 | Immunoglobulin Superfamily Member 2 (CD101) Antibody (PE) | Human | Monoclonal | Mouse | Immunoglobulin Superfamily Member 2 (CD101) | PE | FCM | 487.5 | 100 tests | Q93033 | RUO | |
Abbexa | CD101 | abx139987 | Immunoglobulin Superfamily Member 2 (CD101) Antibody (PE) | Human | Monoclonal | Mouse | Immunoglobulin Superfamily Member 2 (CD101) | PE | FCM | 400 | 100 tests | Q93033 | RUO | |
Abbexa | CD101 | abx139986 | Immunoglobulin Superfamily Member 2 (CD101) Antibody | Human | Monoclonal | Mouse | Immunoglobulin Superfamily Member 2 (CD101) | Unconjugated | WB, IHC-F, FCM, IP | 275 | 0.1 mg | Q93033 | RUO |
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