Family main features
Apolipoprotein C3 (APOC3) is a protein encoded by the APOC3 gene located on chromosome 11 in humans. It is a member of the apolipoprotein C family, which includes APOC1, APOC2, and APOC4. APOC3 is primarily synthesized in the liver and to a lesser extent in the intestine.APOC3 plays a crucial role in lipid metabolism, particularly in the regulation of triglyceride levels in the bloodstream. It functions as an inhibitor of lipoprotein lipase (LPL), an enzyme responsible for the hydrolysis of triglycerides carried by circulating lipoproteins, such as chylomicrons and very low-density lipoproteins (VLDL). By inhibiting LPL activity, APOC3 reduces the clearance of triglycerides from the bloodstream, leading to elevated triglyceride levels. In addition to its role in triglyceride metabolism, APOC3 also interacts with other apolipoproteins and lipoprotein particles, influencing their assembly, remodeling, and clearance. It participates in the regulation of lipid transport and metabolism, contributing to the overall balance of lipids in the bloodstream. The expression of the APOC3 gene is regulated by various factors, including dietary nutrients, hormones, and transcriptional regulators. Factors such as peroxisome proliferator-activated receptors (PPARs), hepatocyte nuclear factor 4 alpha (HNF4α), and insulin influence APOC3 expression levels.Genetic variations in the APOC3 gene can impact its structure, function, and regulation, leading to alterations in lipid metabolism and susceptibility to cardiovascular diseases. Certain APOC3 polymorphisms have been associated with dyslipidemia, characterized by abnormal levels of lipids in the bloodstream, and an increased risk of conditions such as atherosclerosis and coronary artery disease.
APOC3 belongs to the apolipoprotein C family, which includes other members such as APOC1, APOC2, and APOC4. These proteins are essential in lipid transport and metabolism.
Apolipoprotein C3 (APOC3) is a crucial protein in lipid metabolism, primarily involved in the regulation of triglyceride-rich lipoproteins. By inhibiting enzymes like lipoprotein lipase and hepatic lipase, APOC3 prevents the rapid breakdown of triglycerides, maintaining their levels in the bloodstream. Elevated APOC3 levels are associated with hypertriglyceridemia and increased cardiovascular risk, highlighting its significance in lipid homeostasis and disease. Understanding APOC3's function and regulation can provide insights into therapeutic targets for managing lipid disorders and reducing cardiovascular risk.
Apolipoprotein C3 (APOC3)
APOC3, APOCIII, HALP2, apolipoprotein C3, Apo-C3, ApoC-3,apo-CIII, and apolipoprotein C-III,
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con APOC3 - Apolipoprotein C3
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 40 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | APOC3 | abx518727 | Cow Apolipoprotein C3 (APOC3) ELISA Kit | Cow | Serum,Plasma,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P19035 | RUO | ||
Abbexa | APOC3 | abx518728 | Dog Apolipoprotein C3 (APOC3) ELISA Kit | Dog | Serum,Plasma,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P12279 | RUO | ||
FineTest | APOC3 | EH0611 | Human APOC3(Apolipoprotein C-III) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 7.813-500ng/ml | 96T | P02656 | RUO | ||
Abbexa | APOC3 | abx150714 | Human Apolipoprotein C3 (APOC3) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 93.75 pg/ml - 6000 pg/ml | < 45.77 pg/ml | 662.5 | 96 tests | RUO | |
Abbexa | APOC3 | abx253578 | Human Apolipoprotein C3 (APOC3) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 7.81 ng/ml - 500 ng/ml | 4.69 ng/ml | 587.5 | 96 tests | P02656 | RUO |
Abbexa | APOC3 | abx493218 | Human Apolipoprotein C3 (APOC3) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 93.75 pg/ml - 6000 pg/ml | < 40.65 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | APOC3 | abx195166 | Human Apolipoprotein C3 (APOC3) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 78 pg/ml - 5000 pg/ml | 46.9 pg/ml | 618.75 | 96 tests | RUO | |
FineTest | APOC3 | EMK0008 | Monkey ApoC3(Apolipoprotein C3) ELISA Kit | monkey | Busacar en las instrucciones | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P18659 | RUO | ||
Abbexa | APOC3 | abx572477 | Mouse Apolipoprotein C3 (APOC3) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 587.5 | 96 tests | P33622 | RUO |
Abbexa | APOC3 | abx493219 | Mouse Apolipoprotein C3 (APOC3) CLIA Kit | Mouse | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.127 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | APOC3 | abx153663 | Mouse Apolipoprotein C3 (APOC3) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.37 ng/ml | 675 | 96 tests | RUO | |
Abbexa | APOC3 | abx361371 | Pig Apolipoprotein C3 (APOC3) ELISA Kit | Pig | Serum,Plasma,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 0.47 ng/ml | 687.5 | 96 tests | RUO | |
FineTest | APOC3 | ER0741 | Rat ApoC3(Apolipoprotein C3) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 6.25-400ng/ml | 96T | P06759 | RUO | ||
Abbexa | APOC3 | abx575897 | Rat Apolipoprotein C3 (APOC3) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 6.25 ng/ml - 400 ng/ml | 3.75 ng/ml | 531.25 | 96 tests | P06759 | RUO |
Abbexa | APOC3 | abx155221 | Rat Apolipoprotein C3 (APOC3) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.65 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | APOC3 | abx493220 | Rat Apolipoprotein C3 (APOC3) CLIA Kit | Rat | Serum, plasma and other biological fluids. | Sandwich | 1.56 ng/ml - 100 ng/ml | < 0.65 ng/ml | 812.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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Abbexa | APOC3 | abx023247 | Apolipoprotein C3 (Apo CIII) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (Apo CIII) | Unconjugated | ELISA, WB | 2525 | 1 mg | RUO | ||
Abbexa | APOC3 | abx106574 | Apolipoprotein C3 (APOC3) Antibody (FITC) | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | FITC | 162.5 | 20 µg | P02656 | RUO | ||
Abbexa | APOC3 | abx323280 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P02656 | RUO | |
Abbexa | APOC3 | abx171278 | Apolipoprotein C3 (APOC3) Antibody | Human | Monoclonal | Mouse | Apolipoprotein C3 (APOC3) | Unconjugated | WB, IHC, IF/ICC | 750 | 1 ml | RUO | ||
Abbexa | APOC3 | abx105157 | Apolipoprotein C3 (APOC3) Antibody (Biotin) | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Biotin | ELISA | 162.5 | 20 µg | P02656 | RUO | |
Abbexa | APOC3 | abx402497 | Apolipoprotein C-III (APOC3) Antibody | Human | Monoclonal | Rabbit | Apolipoprotein C-III (APOC3) | Unconjugated | ELISA, IHC | 287.5 | 50 µl | P02656 | RUO | |
Abbexa | APOC3 | abx107991 | Apolipoprotein C3 (APOC3) Antibody (HRP) | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | HRP | ELISA | 162.5 | 20 µg | P02656 | RUO | |
Abbexa | APOC3 | abx433648 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Goat | Apolipoprotein C3 (APOC3) | Unconjugated | P-ELISA, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | APOC3 | abx128596 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | WB, IHC, IF/ICC | 262.5 | 100 µl | P02656 | RUO | |
Abbexa | APOC3 | abx376294 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | ELISA, WB, IHC, IF/ICC | 225 | 50 µg | P02656 | RUO | |
Abbexa | APOC3 | abx148246 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | WB | 300 | 50 µl | P02656 | RUO | |
Abbexa | APOC3 | abx109550 | Apolipoprotein C3 (APOC3) Antibody | Human | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | ELISA, WB, IHC | 162.5 | 20 µg | P02656 | RUO | |
Abbexa | APOC3 | abx370273 | Apolipoprotein C3 (APOC3) Antibody Pair | Mouse | Apolipoprotein C3 (APOC3) | ELISA | 1437.5 | 5 × 96 tests | RUO | |||||
Abbexa | APOC3 | abx129320 | Apolipoprotein C3 (APOC3) Antibody | Mouse | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | WB, IHC, IF/ICC | 262.5 | 100 µl | P33622 | RUO | |
Abbexa | APOC3 | abx101716 | Apolipoprotein C3 (APOC3) Antibody | Rat | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | P06759 | RUO | |
Abbexa | APOC3 | abx273274 | Apolipoprotein C3 (APOC3) Antibody (Biotin) | Rat | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | Biotin | WB, IHC, IF/ICC | 375 | 200 µl | RUO | ||
Abbexa | APOC3 | abx131732 | Apolipoprotein C3 (APOC3) Antibody | Rat | Monoclonal | Mouse | Apolipoprotein C3 (APOC3) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | P06759 | RUO | |
Abbexa | APOC3 | abx274084 | Apolipoprotein C3 (APOC3) Antibody (FITC) | Rat | Polyclonal | Rabbit | Apolipoprotein C3 (APOC3) | FITC | WB, IHC, IF/ICC | 437.5 | 200 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | APOC3 | abx065421 | Mouse Apolipoprotein C3 (APOC3) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 225 | 10 µg | P33622 | RUO |
Abbexa | APOC3 | abx166434 | Human Apolipoprotein C3 (APOC3) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | RUO | |
FineTest | APOC3 | P4438 | Recombinant Human Apolipoprotein CIII | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P02656 | RUO | ||
FineTest | APOC3 | P5101 | Recombinant Mouse Apolipoprotein CIII | Mouse | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P33622 | RUO | ||
Abbexa | APOC3 | abx065422 | Rat Apolipoprotein C3 (APOC3) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | P06759 | RUO |
Abbexa | APOC3 | abx655559 | Human Apolipoprotein C3 (APOC3) Protein (Active) | Human | Recombinant | Unconjugated | WB, SDS-PAGE | 537.5 | 50 µg | RUO |
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