UniQ PIIINP RIA
Características de producto
2 – 8 °C
UniQ PIIINP RIA kit is based on the competitive radioimmunoassay technique. A known amount of labelled PIIINP and an unknown amount of unlabelled PIIINP in the sample compete for a limited number of high-affinity binding sites on the antibody. After separating the free antigen, the amount of labelled PIIINP in the sample tube is inversely proportional to the amount of PIIINP in the sample. The concentrations in unknown samples are obtained from a calibration curve.
PIIINP: no cross-reactivity with PINP.
200 µl serum
PIIINP - aminoterminal propeptide of type III procollagen - is liberated into the circulation during soft tissue formation. Changes in PIIINP levels reflect the involvement and altered metabolism of type III collagen, which is common in many connective tissue disorders. PIIINP can be used to assess and monitor fibrotic processes in liver diseases, thus avoiding the need for liver biopsies. It is also useful for monitoring growth hormone therapy in children with growth disorders. PIIINP gives prognostic information on cardiac disease and reflects the healing process.