UniQ ICTP RIA
Características de producto
2 – 8 °C
UniQ ICTP RIA kit is based on the competitive radioimmunoassay technique. A known amount of labelled ICTP and an unknown amount of unlabelled ICTP in the sample compete for a limited number of high-affinity binding sites on the antibody. After separating the free antigen, the amount of labelled ICTP in the sample tube is inversely propor- tional to the amount of ICTP in the sample. The concentrations in unknown samples are obtained from a calibration curve.
ICTP: no cross-reactivity with other UniQ antigens.
100 µl serum
ICTP - carboxyterminal telopeptide of type I collagen - is a crosslinked product of collagen degradation, which is released from bone when it is being degraded under pathological conditions. ICTP can be used to monitor diseases involving pathological degradation of bone, such as cancers that metastasise to bone, rheumatoid arthritis and multiple myeloma