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UniQ ICTP RIA

UniQ ICTP RIA is a quantitative radioimmunoassay designed for measurement of the concentration of carboxytermi- nal cross-linked telopeptide of type I collagen in human serum.

Proveedor

Aidian

Reference

68601

Tested Applications

RIA

Reactivity

Human

Status

CE Marked

Características de producto

tested_applications
RIA
reactivity
Human
category
RIA Kits
size_1
100 test
storage
2 – 8 °C
test_range
1.0‒50 µg/l.
sensitivity
0.6 µg/l
detection_method
UniQ ICTP RIA kit is based on the competitive radioimmunoassay technique. A known amount of labelled ICTP and an unknown amount of unlabelled ICTP in the sample compete for a limited number of high-affinity binding sites on the antibody. After separating the free antigen, the amount of labelled ICTP in the sample tube is inversely propor- tional to the amount of ICTP in the sample. The concentrations in unknown samples are obtained from a calibration curve.
assay_data
ICTP: no cross-reactivity with other UniQ antigens.
availability
Inmediate
dry_ice
No
note
100 µl serum
reserach_area
Colágeno
background
ICTP - carboxyterminal telopeptide of type I collagen - is a crosslinked product of collagen degradation, which is released from bone when it is being degraded under pathological conditions. ICTP can be used to monitor diseases involving pathological degradation of bone, such as cancers that metastasise to bone, rheumatoid arthritis and multiple myeloma