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TSH Canine ELISA

ELISA for the quantitative determination of TSH in canine serum and plasma.

Proveedor

LDN

Reference

ARE8500R

Tested Applications

Elisa

Reactivity

Canine

Status

RUO

Características de producto

tested_applications
Elisa
reactivity
Canine
category
ELISA Kits
size_1
96 test
storage
2 – 8 °C
test_range
0 / 0.2 – 5.2 ng/ml
sensitivity
0.01 ng/ml
assay_data
2 hour 30 min
availability
Inmediate
dry_ice
No
note
100 µl serum or plasma
reserach_area
Animal Research
background
Thyroid stimulating hormone (TSH, thyrotropin) in dogs is similar in function to TSH found in other mammalian species, including humans. It is a glycoprotein produced by the anterior pituitary gland. Through its action on the thyroid gland, it plays a major role in maintaining normal circulating levels of the iodothyronines, T4 and T3. The production and secretion of TSH is controlled by negative feedback from circulating T4 and T3, and by the hypothalamic hormone TRH (thyrotropin releasing hormone). The TSH molecule is composed of two nonidentical subunits,  and , that are bound together in a noncovalent manner. Within a species, the TSH  subunit is structurally identical to the  subunits of the related glycoprotein hormones (LH, FSH and chorionic gonadotropin). The  subunit of TSH and the  subunits of the related hormones are structurally hormone-specific, and account for their unique biological activities.