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Prolactin Canine ELISA

ELISA for the quantitative determination of prolactin in canine serum.

Proveedor

LDN

Reference

ARE8400R

Tested Applications

Elisa

Reactivity

Canine

Status

RUO

Características de producto

tested_applications
Elisa
reactivity
Canine
category
ELISA Kits
size_1
96 test
storage
2 – 8 °C
test_range
0 / 2.5 – 80 ng/ml
sensitivity
0.4 ng/ml
assay_data
3 hour 30 min
availability
Inmediate
dry_ice
No
note
25 µl serum
reserach_area
Animal Research
background
Canine prolactin (cPRL) is a single-chain polypeptide hormone of the canine anterior pituitary with a molecular mass of approx. 22,000. Prolactin from different species exhibits significant variations in the amino acid sequence. Canine prolactin differs from human prolactin at about 60 percent of all residues. The secretion of cPRL from the pituitary is inhibited by hypothalamic prolactin-inhibitory factor (PIF). Although dopamine was long thought to be this PIF molecule, today it seems that there is a special peptide with prolactin-inhibiting activities. The release of prolactin is certainly stimulated by different peptides, particularly thyrotropin releasing hormone (TRH) and vasocative intestinal peptide (VIP). Estrogens and progesterone also seem to play a role in the secretion of prolactin, and neurogenic factors influence its release. Milking and suckling are immediately followed by an increase in serum cPRL.