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Progesterone Mouse/Rat

ELISA for the quantitative determination of progesterone in rat and mouse serum and plasma.

Proveedor

LDN

Reference

ARE8700R

Tested Applications

Elisa

Reactivity

Rat/Mouse

Status

RUO

Características de producto

tested_applications
Elisa
reactivity
Rat/Mouse
category
ELISA Kits
size_1
96 test
storage
2 – 8 °C
test_range
0 / 0.4 – 100 ng/ml
sensitivity
0.156 ng/ml
assay_data
1 hour 30 min
availability
Inmediate
dry_ice
No
note
10 µl serum or plasma
reserach_area
Animal Research
background
Progesterone (4-pregnene-3, 20-dione) is a C21 steroid hormone containing a keto-group (at C-3) and a double bond between C-4 and C-5. Like other steroids, it is synthesized from cholesterol via a series of enzyme-mediated steps (1). Progesterone is a female sex hormone of primary importance in ovulation, fertility and menopause. It is particularly important in preparing the endometrium for the implantation of the blastocyte and in maintaining pregnancy (2). The rate of progesterone secretion may be affected by the degree of progestational activity of the uterus and the level of circulating LH (3). Analyses suggest that progesterone acts as an anti-glucocorticoid in rat adipose tissue in vivo, attenuating the glucocorticoid effect on adipose tissue metabolism (4). Furthermore it could be demonstrated that progesterone alone may be a valuable agent for management of postmenopausal osteoporosis (5). In female rodents, the determination of progesterone is a useful marker in evaluating and monitoring the state of the reproductive functions and pregnancy as well.