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Melatonin ELISA

Enzyme immunoassay (ELISA) for the quantitative determination of melatonin in serum and plasma.

Proveedor

LDN

Reference

BAE3300

Tested Applications

Elisa

Reactivity

Human

Status

CE Marked

Características de producto

tested_applications
Elisa
reactivity
Human
category
ELISA Kits
size_1
96 test
storage
2 – 8 °C
test_range
0 / 3.0 – 300 pg/ml
sensitivity
1.6 pg/ml
assay_data
Extraction 15min; ELISA overnight; 2 hours 40 min
availability
Inmediate
dry_ice
No
note
500 µl serum or plasma
reserach_area
Melatonin
background
The pineal gland (corpus pineale) has been called a neuroendocrine transducer because of its important role in photoperiodism. The major hormone of the pineal gland is N-acetyl-5-methoxy-tryptamine or melatonin which is synthezised from the amino acid tryptophane. Melatonin has its highest levels in plasma during nighttime. Its characteristic nocturnal surge appears to encode temporal information such as length of night. Regulation of the melatonin secretion is under neural control. Sympathetic innervation seems to play a major role via its release of noradrenaline. Altered patterns and/or levels of melatonin secretion have been reported to coincide with sleep disorders, jet lag, depression, stress, schizophrenia, hypothalamic amenorrhea, pregnancy, anorexia nervosa, some forms of cancer, immunological disorders as well as control of sexual maturation during puberty