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LDBIO Toxo II IgG Confirmation

450,00 (12 test)

LDBIO TOXO II IgG is a qualitative test of serological IgG diagnosis by immunoblot assay of toxoplasmosis intended for confirmatory testing of a positive or equivocal result obtained through classic screening tests. It can be performed on sera, cerebrospinal fluid (CSF) or aqueous humor.

Proveedor

LD Bio

Reference

TOXOII12G

Tested Applications

WB

Reactivity

Human

Status

CE 0459

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Características de producto

tested_applications
WB
reactivity
Human
category
Western Blot
size_1
12 test
size_2
24 test
size_3
96 test
storage
2 – 8 °C
detection_method
The Toxoplasma gondii antigens, once separated by electrophoresis, are electrotransfered to the surface of a nitrocellulose membrane which is cut into numbered strips
assay_data
This assay is not intended for congenital toxoplasmosis diagnosis by comparison of immune profiles. For that application, use the TOXOPLASMA WB IgG-IgM test instead (ref. TOP-WBGM).
availability
Inmediate
dry_ice
No
note
10 µl serum ,CSF or aqueous humour
reserach_area
Toxoplama
background
The determination of a primary infection may be easy if the patient’s serological history is known, or more complex in the case of a first positive sample during pregnancy. In this case, several indicators, all imperfect, can be used: the presence of IgM, the avidity of IgG, the presence of IgA (Olariu et al., 2019), the evolution of the antibody titer (Montoya et al.,2008). The presence of IgM, as most commonly detected by ELISA, is theoretically a marker of primary infection but lacks specificity (Villard et al., 2016a) and residual IgM is detected in a significant number of cases: 1 year after infection between 9 and 27% of patients may still have detectable IgM (Villard et al., 2016b). Avidity of IgG also allows a dating and excludes a recent infection in case of high avidity. However, some patients never develop high avidity so a low avidity does not indicate a recent infection. Finally, a significant increase in IgG levels between 2 samples two weeks apart is in favor of a recent infection. Conversely, stable IgG levels indicate an infection older than 3 months (Villard et al., 2016b).