Human Prostaglandin E2 Receptor EP2 Subtype (PTGER2) CLIA Kit
845€ (96 tests)
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935106861
info@markelab.com
name
Human Prostaglandin E2 Receptor EP2 Subtype (PTGER2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx491285
tested applications
CLIA
Description
Human Prostaglandin E Receptor 2 (EP2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Prostaglandin E2 Receptor EP2 Subtype (PTGER2) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78.12 pg/ml - 5000 pg/ml |
| Sensitivity | < 29 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | PTGER2,PGE receptor EP2 subtype,prostanoid EP2 receptor,Ptger-ep2,prostaglandin E receptor 2 (subtype EP2) |
| Background | CLIA Kits PTGER2 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTGER2, or EP2, is a G protein-coupled receptor activated by prostaglandin E2 (PGE2), a major lipid mediator involved in inflammation, immune modulation, and tissue repair. EP2 primarily couples to Gs proteins, leading to the activation of adenylate cyclase, increased cAMP levels, and downstream signaling that modulates cell survival, vasodilation, and immune responses. EP2 is expressed in immune cells, vascular smooth muscle, and epithelial tissues, where it promotes anti-inflammatory effects, smooth muscle relaxation, and vasodilation. In the central nervous system, EP2 mediates neuroprotection and contributes to synaptic plasticity. Dysregulation of EP2 signaling has been linked to inflammatory diseases, neurodegeneration, and cancer, where EP2 activation enhances tumor growth and immune evasion. EP2 agonists are being explored for their neuroprotective and anti-inflammatory properties, while antagonists are being investigated to inhibit tumor progression and chronic inflammation, particularly in conditions such as arthritis and neurodegenerative disorders.
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