Human Insulin Like Growth Factor Binding Protein 4 (IGFBP-4) CLIA Kit

CLIA

Human

CLIA Kits

Insulin Like Growth Factor Binding Protein 4 (IGFBP-4)

96 tests

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

0.625 ng/ml - 40 ng/ml

0.38 ng/ml

Chemiluminescent

Sandwich

Quantitative

Shipped within 5-12 working days.

No

This product is for research use only.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4 gene. This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. It is secreted by all colon cancer cells. Target